Randomised trials and ribavirin.
نویسنده
چکیده
with severe respiratory syncytial virus infection. Crit Care Med 1987;15:1051-4. 13 Gelfand EW, McCurdy D, Pandu Rao C, Middleton PJ. Ribavirin treatment of viral pneumonitis in severe combined immunodeficiency disease. Lancet 1983;ii:732-3. 14 McIntosh K, Kurachek SC, Cairns LM, Burns JC, Goodspeed B. Treatment of respiratory viral infection in an immunodeficient infant with ribavirin aerosol. Am J Dis Child 1984;138: 305-8. 15 McMillan JA, Tristram DA, Weiner LB, et al. Prediction of the duration of hospitalization in patients with respiratory syncytial virus infection: use of clinical parameters. Pediatrics 1988;81: 22-6. 16 Wyde PR, Wilson SZ, Petrella R, Gilbert BE. Efficacy of highdose-short duration ribavirin aerosol treatment of respiratory syncytial virus infected cotton rats and influenza B virus infected mice. Antiviral Res 1987;7:211-20. 7 Isaacs D. Ribavirin. Pediatrics 1987;79:289-91.
منابع مشابه
Interferon alfa with or without ribavirin for chronic hepatitis C: systematic review of randomised trials.
OBJECTIVE To assess the efficacy and safety of interferon alfa with or without ribavirin for treatment of chronic hepatitis C. DESIGN Systematic review of randomised trials on interferon alfa plus ribavirin combination therapy versus interferon alfa. Patients were naive (not previously treated with interferon), relapsers (transient response to previous interferon therapy), or non-responders (...
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Introduction: Based on data from recent trials, peginterferon and ribavirin combination therapy is the standard of care in treating patients with chronic HCV infection, but because of high costs, many patients may deprive from treatment. Methods: We conducted a clinical trial on HCV patients in Yazd in gastroenterology clinic. Thirty patients received conventional subcutaneous interferon alf...
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OBJECTIVES To determine whether antiviral therapy reduces the risk of developing hepatocellular carcinoma (HCC) in chronic hepatitis C. DESIGN Systematic review and meta-analyses of randomised controlled trials. Prospective cohort studies were included in sensitivity analyses. DATA SOURCES Eligible trials were identified through electronic and manual searches. STUDY SELECTION Eight random...
متن کاملRetreatment of hepatitis C non-responsive to Interferon. A placebo controlled randomized trial of Ribavirin monotherapy versus combination therapy with Ribavirin and Interferon in 121 patients in the Benelux [ISRCTN53821378]
BACKGROUND Evidence based medicine depends on unbiased selection of completed randomized controlled trials. For completeness it is important to publish all trials. This report describes the first large randomised controlled trial where combination therapy was compared to placebo therapy and to ribavirin monotherapy, which has not been published until now. METHODS One hundred and twenty one pa...
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ورودعنوان ژورنال:
- Archives of disease in childhood
دوره 63 8 شماره
صفحات -
تاریخ انتشار 1988